Born and raised in Jackson, Tennessee, Pritchard began writing songs when she was 14 years old. She then moved to Los Angeles at 16, where she lived with Lisa Marie Presley and tried to make it as a singer in a reggae band. She eventually succeeded as a musical actress, by originating and playing the role of the 15-year-old runaway "Ilse" in the hit Broadway show Spring Awakening for two years.
Pritchard later settled in the United Kingdom, and signed with Universal/Island Records. In August 2010 she released the single "Painkillers", and the song was also released in a remix with rapper Talib Kweli. Her debut album, Wasted in Jackson, written and produced with Eg White, was digitally released on October 25, 2010 and debuted at No. 84 in the UK. It was also scheduled for physical release in the US on February 22, 2011. Pritchard mentions Billy Joel, Joni Mitchell, Al Green and Candi Staton as some of the influences behind her music.
In 2013, Pritchard adopted the stage name Lolo and has since signed with DCD2 Records. "Under her given name, Pritchard is also the composer-lyricist of the new musical Songbird..."
In 2013 she began opening for the alternative band Panic! at the Disco. She still opens for live concerts and tours with the band. She was also featured on the Panic! at the Disco song, "Miss Jackson".