The Gutter Twins is a musical collaboration between rock musicians Greg Dulli and Mark Lanegan. Dulli and Lanegan have regularly contributed to each other's projects since 2000, most notably in Dulli's Twilight Singers; of the duo's origins, Dulli said "I think Mark told a journalist we were doing it, and then the journalist called me, and I didn't know we were doing it." On Christmas Day 2003, Dulli and Lanegan began work on the collaboration.
In July 2007, the music website Pitchfork Media announced that the duo, "two of the alt-rock era's greatest frontmen," had signed to Seattle label Sub Pop. Soon thereafter, Sub Pop reported a 4 March 2008 release date for their debut album Saturnalia.
The Gutter Twins appeared with their backup band on the Late Show with David Letterman on March 20, 2008, and toured the album throughout the USA and Europe during the year. Critical response to the album was consistently good; Blast Magazine called it "an audial descent into the dark emotions that often lurk beneath the surface." and that "The haunting Gods Children sounds like it was penned by U2s long-lost cousin from Seattle". and Uncut said "With Lanegan at his stentorian best and Dulli in full confessional mode, Saturnalia is a feast, certainly but one where the dishes are served delightfully raw."
In September 2008, The Gutter Twins released the Adorata EP through iTunes. It features two original songs and cover versions of songs by Jos Gonzlez, Primal Scream, Scott Walker, Vetiver, and Eleven. A portion of Adoratas proceeds will go to the Natasha Shneider Memorial Fund. Shneider was a friend of the band and the late lead singer of Eleven.